Generic name: Tianeptine

Classification

Antidepressants

Indications

Major depressive disorders, anxio-depressive states.

Dosage

3 tab daily (1 in the morning, 1 at noon & 1 in the evening) before meals.

Contraindications

Childn under 15 yrs old. Association w/ MAOIs. A washout period of 2 wks is necessary between treatment w/ MAOIs & treatment w/ tianeptine. A washout period of only 24 hrs is reguired when replacing tianeptine w/ a MAOI.

Precautions

Pregnancy, lactation. Keep patient under medical supervision during the initial phase of treatment as a risk of suicide exists in depressive patients. May affect ability to drive or operate machinery. If the treatment is to be interrupted the dosage should be gradually reduced. Stop the drug 24 to 48 hr prior to surgery w/ general anesthesia.

Adverse Reactions

Rare & non-severe: Epigatric pain, abdominal pain, nausea, vomiting, constipation, insomnia, drowsiness, asthenia, dry mouth, tachycardia, extrasystoles, vertigo, headache, lipothymia, tremor, hot flushes, resp discomfort, mialgia, back pain.

Interactions

MAOIs.